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  • A New Type Of Protein That Can Reduce Obesity And Diabetes In Humans

    09. August 2011

    type 2 diabetes

    A type 2 diabetes illustration. (Photo: topnews.in)

    Obesity, will not require an introduction as it is somewhat of a widespread catastrophe, that affects millions to billions of people on a global scale. Even though a lot of countries have a different definition, an obese man is commonly classified as a person who has a body mass index (BMI) of 30 units or more and as for an overweight person, the BMI rating should be in the 25-30 range. So while obesity may delude a person to believe he is healthy, it is the chief cause of various cardiovascular diseases and diabetes to the point where nearly 40 percent of all obese people are known to diabetic. But fortunately for them, a new study by the New york state university, suggests that obesity and diabetes can be controlled and maintained with the help of a simple, albeit easy to get, protein compound.

    According to professor Suraj Unniappan, who is the associate professor at the biology section of the institute, the use of a common mammalian protein known as the Nesfatin-1 may add some hope for diabetic people who are also obese. Nesfatin-1 is a protein compound that is commonly found in the brain of mammalian animals, including humans. Dr Unniappan, who had previously conducted an experiment with a group of lab rats and mice , found out that they could lose their excess weight by storing fat efficiently after they were administered with a strong nesfatin-1 dose. The protein was also able to stimulate the pancreatic beta cells in the rats, which allowed it to secrete enough insulin to fight of the diabetes.

    As professor Unniappan puts it, the nesfatin-1 protein can stimulate a certain number of cells in the human pancreas, called the islets of Langerhans, which in turn would produce enough insulin to fight of type 1 and type 2 diabetes. However, the professor and his team are still testing on its effect on humans. The gut-brain axis, which is Dr Unniappan’s own coinage, suggests the relationship between the peptides in the brain, which are responsible for thinking, and the peptides in the gut, which are responsible for the endocrine production for the body. So ,while the gut brain axis still needs to be carefully analyzed , they show a strong evidence of the link between diabetes and obesity.

    If this research turns out to be successful, the world may finally have a cure than can help the unfortunate ones get rid of obesity and diabetes simultaneously. But since excess levels of protein is never good for the body, the researchers should meticulously test their side effects on humans, before they create a nesfatin-1 protein based commercial drug. So for the time being, all we can do is stay healthy using the traditional mantra of eating right and avoiding the consumption of excess sugars.


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